Casts : Ellen Pompeo, Sandra Oh, Justin Chambers
Covering days one through 13, everyone at Seattle Grace fights to save Izzie and George’s lives and then deals with the aftermath. Elsewhere, Hunt treats a double amputation, and Arizona has a teen with painful growth spurts.
During days 20 through 40 the staff continues toward acceptance. Meanwhile, Arizona takes a manipulative step to diagnose her pain patient and Hunt’s amputee patient sinks into a deep depression.
As hospital personnel jockey for notice to keep from being fired, Izzie returns to surgery early and Bailey’s triple aneurysm patient refuses her procedure because of her schizophrenic son.